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peaches2881
«I have been taking Estratest H.S. 0.6251.25mg for 18 yes now and all of my hot flashes, night sweats, mood swings they all have went away. But since I smoke my drs here in Missouri will not give them too me until I have stopped smoking for at least 3 months. That is easier said then done. Without my pills I get migraine headaches, crazy mood swings and I can't stand to be around myself.»
Northeastspot
«This medication is a miracle. Hot flashes and sweats go away, sleep has returned, and I have more energy and clearer thinking. It helps with libido as well. I did notice some hair loss, which surprised me, but overall no other side effects. The major problem with estratest hs is the requirement for a one month prescription, you can no longer get a 3 month supply which would save money, and you have to call the doctor every month to get a new prescription. For women who are menopausal, I find this to be ridiculously inconvenient and costly. Regulations need to be adjusted to accommodate us ladies who need this medication to function. Medicare doesn't cover this med, apparently.»
rosebud1945
«After trying every other hormone. The Doctor put me on methyltestosterone F S. I have been on this drug for 20 yrs now. My Insurance will not pay for it.It is the only hormone that works for me. I type this now because I stop taking 10 days a go thinking 70 years old I would not need them. At this time I am in hot flashs, sweats and can not sleep. I will be making a appointment with my Doc ASAP. Do not think your to old to need estrogens and testosterones.»
Anonymous
«I had a complete hysterectomy and the hot flashes & night sweats were terrible. Plus I didn't have a sex drive like I use to. I was taking Premarin but it was costing me $30.00 a month with insurance. But the pharmacist said this worked the same way the Premarin worked. It's the 0.625mg Esterified Estrogens & 1.25mg Methylteosterone. I have been taking it for a couple of yrs and it works. I have no night sweats or hot flashes and I have sex whenever I want it. This hormone therapy only cost me $10.00 with my insurance. I am satisfied with this therapy.»
dolores1757
«As most women have said I feel 100% better. Before taking this I must have had very symptom you could possibly think of, except the hot flashes which I think I would have rather suffer through than all the others.»
betternow
«About ten days or two weeks after starting Estratest HS, I felt like myself again. Hot flashes are now gone completely (after two months on it), my skin looks like it used to look, and I have my old desire back (hubby is thrilled too). I feel more energy and stronger over all. I can do more at the gym. The only drawback was weight gain, but all the other good results more than make up for it.»
Anonymous
«I finally found something that worked for me- before I was having difficulty finding the right dose- now that they no longer make it, I am have a difficult time taking the generic due to the noticeable side effects- but the alternatives do not work either.»
dunerd
«I had been taking Estratest HS in combination with Premarin.3 for the last 12 years and loved, loved, loved it. No side effects. Made me feel stronger and helped keep my body in shape. Since they no longer make it, I have been having trouble adapting to new hormones and wish I could find some kind of testosterone substitute.»
Low Test
«Had low testosterone. I was in a car accident and had a head injury. This caused my pituitary gland to stop working and shrank from the pressure in my brain. I didn't want a patch. I inject every 2 weeks and it works great. It's much cheaper, nobody has to know unless you tell them and it takes 5 minutes every 2 weeks. What could be easier.»
Alice8
«I had a hysterectomy (total) in 2012. Since then I have had decreased hormones (they gave me estradiol in increasing dosages with no help). The beginning of this year my urologist ran very specific tests, I had very little estrogen (I was not absorbing the estradiol pills full strength, it was being wasted thru digestion), so he put me on Divigel (estrogen gel, to apply to my upper thigh area daily). The other parts of female hormones I had absolutely None of were progesterone and testotestosterone (I didn't know that women produced it also, and is very important to severe hot flashes and severe mood swings.) I cannot live a normal life without it, I get completely crazy without the small pea sized dose I smear on my calf every day.»
Southern Guy
«I had T levels below 200 and the Doc started me on Androgel 1.62. I saw minor improvements at 2 and 3 pumps per day, but didn't see normal T numbers until he prescribed a max dose of 4 pumps daily. I had libido and ED issues that have greatly improved. The main side effect I have is that I have some body acne on the shoulders and upper chest, I've also had a little more chest hair. Without insurance and even with insurance the gel can be too pricey for many.»
fin300
«shots: 250 mg a week and I'm like a 18 years young man. wife is happy and I have lots of energy and good mood swing»
Horse With No Name
«I tried Testim samples and found its fragrance revolting and it did not dissipate through the day. I cannot imagine smelling as if I applied cologne every day of my life. And I really ripped into the manufacturer's stupidity on their website. One thing any man with hypogonadism wants is for no one but his doctor and lover to know he has hypogonadism. Walking around with the same strong scent everyday would be odd in an office environment and no doubt someone would ask what the cologne name is. It is so thoughtless.»
David P.
«Works great. Was experiencing adverse effects of low T and my doctor confirmed it. He prescribed this to me as 2 pumps per leg per day. At first it took about 45 minutes to absorb but now it takes about 5-10 minutes and goes on easily. My wife now complains that my libido is too strong LOL. I love this. I hope you have similar experience as I do. My insurance didn't want to cover the other popular brands. The Pharmacy specialist in my insurance told me to go for this as they would cover it right off the bat. Glad I spoke to them. Just $20.00 per two bottle refills.»
Jwright7784
«I was struggling pretty bad with chronic daily fatigue and a foggy head. After eliminating a few possibilities as to the cause I discovered low testosterone can cause these types of issues. I asked my doctor to be tested and sure enough I was low. My levels were actually lower than a 75 year old man (I was 30 at the time). Tried the gel, it worked but I didn't really like it. I was switched to the patches. The patches would not, for the life of me, stay on. Finally I was placed on the injection. The injection works great for me. I can do it in the comfort of my own home and I only have to do it once every 2 weeks. My wife was trained by a nurse on how to give the shots and that's how we do it. My levels are now within normal range.»
Anonymous
«I had abnormally lot T readings, 199, 225 and 249, went on Androgel Brand name therapy, within a month, subsequent readings over 400, last reading was 76, and the only difference is that I was swiched to a generic brand, Perrigo, from Israel.»
Dirk Diggler
«This is a compound drug that comes in a kit. The pharmacist behind the counter will mix it before dispensing it. It's a cheap cream that comes in a jar like coco butter and you put it on your shoulders. It's very difficult to get the correct dosage with a cream so that's why it didn't work for me. A gel is much better than cream, but the cream is cheaper.»
Chris t
«Received my first shot yesterday in term of effectivity I'm not sure yet however I did have some severe side effects following the injection. Dizziness, sweating, and I fainted however it passed in about 10 minutes.»
Brett77
«I had used testosterone injection therapy with mixed results. My doctor was concerned about possible heart attacks in an article he read, so he switched me to Axiron. I took it 4 or 5 months. I did not find Axiron hard to apply other than waiting 3 minutes between deodorant and application. Sometimes, I felt a bit warm as far as body temperature afterwards. The problem was, it didn't work for me. Sexual function got worse and worse, and I just had a blood test where my testosterone was 105, horrendously low for mid 40's person. So basically, my body does not absorb it.»
MPW61
«I am a 54 year old male; my free T came back at 29, very low. I was prescribed 1.62% less then a week ago. My motivation and energy levels coming back up already. I have no sex drive at al and cannot get or maintain an erection. Anxious to see how things progress in a couple weeks. Thanks to all for the great feedback.»
Skeetman
«Just 3 days in on using Testim and with all the negative reviews I was worried. The application process is not a big deal to me and while sticky it drys quickly and my shirts don't stick. My wife noticed the smell but thought it smelled manly and no one else has commented yet. I barely notice it even having asthma. Reallly no apparent changes yet but today I had an itch on the side of my penis and started scratching it and almost in no time I was semi erect so I guess that's a good first step. My Urologist told me to expect changes after 5-6 days so we'll see.»
kethouse
«this is a real scam ! it not work !»
Misha707
«Worked well on restablishing "normal" testosterene levels, but strong impact on moods,,agresiveness and irritability.»
Yayostyle
«I have been using testim for 6 years now due to endocrine induced low testosterone count. Overall it has increased my libido and the smell is great to women. I take half tube per day (about 25mg). However, I experience joint pain all the time notably on my fingers obviously used to rub the stuff on my shoulders. I also feel pain under my feet. Getting up and trying to walk in the morning is a struggle. The symptoms disappear after 15-20 minutes. And the joint pain is less noticeable in summer when it's warmer. Last year I slipped and fell on my shoulder resulting in a comminuted fracture. I'm worried testim might be causing osteoporosis. My endocrinologist and Dr are aware of my symptoms but haven't offered any explanation to date.»
XXYGuy
«I've taken testosterone in various different forms since I was 18, and the worst form was the implants as my body rejected them, twice, so I gave up on that method. Recently the manufacturers of Andriol have advised production of Andriol was going to be delayed and New Zealand won't be restocked until September 2016. Not wishing to go back to injections I determined to trial Androderm patch, and I wish I'd done it years ago. My skin has no reaction to this patch. It delivers a good level of testosterone based on how I feel, I've not had any blood tests to back that opinion up. However; on Andriol I don't experience morning erections very often, but with the patch I do, regularly. Shaving has also gone back to normal.»
SF Guy
«I've been using this for a few years and have had a great experience. More energy and I think also helped with mild depression. About the odor- to ME it smells chemical and harsh putting it on, but once it's on can't smell it. SOME people don't smell it on me at all. SOME people think it smells great on me. A lot of women who are candid enough to tell me ~really~ like it. The moral of the story is that the smell as experienced by the person smelling it is highly variable. Clearly it has something to do people's biochemical attractions. Note there are studies about women smelling men's worn clothing (without cologne or anything) and there's a wide variety of reactions and attraction.»
DoesNotWork
«I have been using Axiron for 3 months and have experienced no noticeable positive effects. Still have low libido, no morning erections, lack of penile sensitivity, weak orgasms and lethargy. Going to try injections ASAP.»
C'mon Friday
«As a not-so-active 54 year old male who is a non-smoker and relatively light social drinker, my T level had dropped to a pathetic 120. I had no mojo for anything and my doctor commented out load how she wondered how I got out of bed in the morning. After 3 years of Axiron therapy (underarm application) I am at a very comfortable 900. I feel so much better and while my marriage did not survive this condition, my girlfriend is enjoying the benefits of this replacement therapy. It works for me (and my woman!).»
DonnieDP
«Androgel gave me a rash and my doctor prescribed this to me. I am supposed to apply 2 tubes but this is simple disgusting. It has a very strong sweet odor that never leaves your body. I absolutely hate it, everywhere I go I reek of this smell. Not sure what genius thought of this idea that something that has to be applied by millions people is supposed to have a fragrance. Secondly and this is bad too, it's disgusting to put on compared to androgel. It's more sticky / oily and never fully gets in the skin. I keep rubbing it for 10 minutes and still the outer layer of my skin is greasy and it never dries. It will probably work but I am going back on injections as I can't get over the smell / substance issues.»
oldguyaz
«Looking at these different reviews I have to make a comment. I was placed on low T therapy in 2005. Tried Testim & Androgel, couldn't tolerate them, was refererred to a compounding pharmacy who produce whats called a bio identical testosterone gel, measured dose with a small spoon and applied to the skin, in my case upper forearms. Works great, no skin irritation, dries in a couple minutes, not sticky, clear in color, slight alcohol smell, bad thing insurance won't cover it, good thing it currently only costs $48. For a 30 day supply. Been using it now for 10 years.. might not be for everyone but worth a try if you are not getting positive results with the other products..»
Eddie St J
«I've done well on Testim. Energy and mood levels up. Really helps in the gym, too. Lifting weights enhances the effect, probably because lifting helps augment T. Many women love the smell. I get lots of comments about it. In fact, it's pretty funny.»
stickyone
«Was forced to use Testim gel as my new insurance would not cover Fortesta or Androgel. This stuff is disgusting. NEVER completely dries...If I apply in the morning, even after an hour wait, my shirt sticks to me like glue. If I apply at night, MY SHEETS STICK TO ME. Smells terrible, extremely difficult to apply (comes in small metal tubes and nearly impossible to get it all out) and worst of all, did not raise my testosterone levels significantly. I dreaded applying this.»
jbrown9999
«Started using this less than a week ago. I've done test inj in the past and worked out and got dramatic results. Now that I'm older (48), my test is low, 208, my Dr prescribed Androgel, but insurance only covers Testim. Personally, I think it smells like Lysol. I am feeling better but hate the application process and the stickiness off my skin afterward. If my levels don't bump up on my next round of blood tests, I'm going to go to a urologist and see about getting the pellets put in.»
Low Test
«Had low testosterone. I was in a car accident and had a head injury. This caused my pituitary gland to stop working and shrank from the pressure in my brain. I didn't want a patch. I inject every 2 weeks and it works great. It's much cheaper, nobody has to know unless you tell them and it takes 5 minutes every 2 weeks. What could be easier.»
Mike Asti
«You need to check your hormones with blood work to make sure they are all level. After using depo tesoesterone for a while.you will start feeling side effects you never got before. Also you might have to donate your blood testosterone will give you a high red blood cell count which it's not good. When you notice your test shots are not giving you the most like it used to you have high estrogen levels and prolactin levels too. you will need to take arimidex to bring it down. You will know when it's time the side effects are terrible. vitamin D is recommended while taking depo testerone it's a must.»
Would highly recommend
«I had suffered from anxiety and depression (suicidal grade) since I was a boy. I first began taking anti-depressants at age 12. My doctor had a chart in her office about low T, it listed 10 symptoms. I had all 10. I asked her to prescribe it. So, she did all of the required tests. I was within the average range. 7 years later same results, I am now 48. Finally in January of 2014, I said that I would chance any side effect. My tests had come back normal yet again. But, she did prescribe it. I woke up on day 14 with NO depression or anxiety. What can I say, 48 years of existing and my brain chemistry is now great. My energy level is incredible and depression simply doesn't happen. It is quite a miracle. Get it!»
Hedmed
«I am a 43 year old that works out 5 times a week for 1-1.5 hours each time. Woke up one morning about 3 months ago and felt like somebody turned off a switch in my body, no real desire for sex but after a lot of foreplay able to somewhat achieve an erection but not really hard. Went to Dr and testosterone of 188. Started on Depo Testosterone by IM injection in gluteus and 4 hours after first dose was able to achieve an erection that I would describe at times as almost a little painful due to how hard I was and able to perform 4 times that day with wife. Not sure of effects at gym yet due to only being the 3rd day since beginning shot- 200mg every other week. Didn't have any of the other issues ie depression, anxiety, lethargy prior.»
Dirk Diggler
«This is a compound drug that comes in a kit. The pharmacist behind the counter will mix it before dispensing it. It's a cheap cream that comes in a jar like coco butter and you put it on your shoulders. It's very difficult to get the correct dosage with a cream so that's why it didn't work for me. A gel is much better than cream, but the cream is cheaper.»

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ANADOIL-40 (5-androstene-3b-17b-Diol)
5-Androstenedoil-Designed to dramatically increase levels of testosterone in the human body. The substance 5-Androstene-3b-17b-Doil is a hormone precursor that has a direct one-way conversion into testosterone in the body.
5-AD is actually the demethlated version of the schedule III ANABOLIC STEROID METHANDROIL.
Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands. It is the principal male sex hormone and an anabolic steroid.
In both men and women, testosterone plays a key role in health and well-being as well as in sexual functioning. Examples include enhanced libido, increased energy, increased production of red blood cells and protection against osteoporosis. On average, an adult human male body produces about forty to sixty times more testosterone than an adult female body, but females are, from a behavioral perspective (rather than from an anatomical or biological perspective), more sensitive to the hormone. However the overall ranges for male and female are very wide, such that the ranges actually overlap at the low end and high end respectively.
Virilizing and effects on humans
In general, androgens promote protein synthesis and growth of those tissues with androgen receptors. Testosterone effects can be classified as virilizing and anabolic, although the distinction is somewhat artificial, as many of the effects can be considered both.
— Anabolic effects include growth of muscle mass and strength, increased bone density and strength, and stimulation of linear growth and bone maturation.
— Virilizing effects include maturation of the sex organs, particularly the penis and the formation of the scrotum in unborn children, and after birth (usually at puberty) a deepening of the voice, growth of the beard and axillary hair. Many of these fall into the category of male secondary sex characteristics.
Testosterone effects can also be classified by the age of usual occurrence. For postnatal effects in both males and females, these are mostly dependent on the levels and duration of circulating free testosterone.
Prenatal androgen effects
Most of the prenatal androgen effects occur between 7 and 12 weeks of gestation.
— Genital virilization (midline fusion, phallic urethra, scrotal thinning and rugation, phallic enlargement); although the role of testosterone is far smaller than that of Dihydrotestosterone.
— Development of prostate and seminal vesicles
Early infancy androgen effects
Early infancy androgen effects are the least understood. In the first weeks of life for male infants, testosterone levels rise. The levels remain in a pubertal range for a few months, but usually reach the barely detectable levels of childhood by 4-6 months of age. The function of this rise in humans is unknown. It has been speculated that «brain masculinization» is occurring since no significant changes have been identified in other parts of the body.
Early postnatal effects
Early postnatal effects are the first visible effects of rising androgen levels in childhood, and occur in both boys and girls in puberty.
— Adult-type body odour
— Increased oiliness of skin and hair, acne
— Pubarche (appearance of pubic hair)
— Axillary hair
— Growth spurt, accelerated bone maturation
— Develop hair on upper lip and sideburns.
Advanced postnatal effects
Advanced postnatal effects begin to occur when androgen has been higher than normal adult female levels for months or years. In males these are usual late pubertal effects, and occur in women after prolonged periods of heightened levels of free testosterone in the blood.
— Phallic enlargement or clitoromegaly
— Increased libido and frequency of erection or clitoral engorgement
— Pubic hair extends to thighs and up toward umbilicus
— Facial hair (sideburns, beard, moustache)
— Chest hair, periareolar hair, perianal hair
— Subcutaneous fat in face decreases
— Increased muscle strength and mass
— Deepening of voice
— Growth of the Adams apple
— Growth of spermatogenic tissue in testes, male fertility
— Growth of jaw, brow, chin, nose, and remodeling of facial bone contours
— Shoulders become broader and rib cage expands
— Completion of bone maturation and termination of growth. This occurs indirectly via estradiol metabolites and hence more gradually in men than women.
Adult testosterone effects
Adult testosterone effects are more clearly demonstrable in males than in females, but are likely important to both sexes. Some of these effects may decline as testosterone levels decline in the later decades of adult life.
— Libido and clitoral engorgement/penile erection frequency.
— Mental and physical energy
— The most recent and reliable studies have shown that testosterone does not cause Prostate cancer, but that it can increase the rate of spread of any existing prostate cancer. Recent studies have also shown its importance in maintaining cardio vascular health.
— Increase eumelanin and reduce pheomelanin
Testosterone regulates the population of thromboxane A2 receptors on megakaryocytes and platelets and hence platelet aggregation in humans ( Ajayi and Halushka 2005, Ajayi et al 1995).
Effects on the brain
As testosterone affects the entire body (often by enlarging; men have bigger hearts, lungs, liver, etc.), the brain is also affected by this «sexual» advancement; the enzyme aromatase converts testosterone into estradiol that is responsible for masculinization of the brain in a male fetus.
There are some differences in a male and female brain (the result of different testosterone levels). A clear difference is the size: the male human brain is, on average, larger; however, in females (who generally do not have as high testosterone levels) the corpus callosum is proportionally larger. This means that the effect of testosterone is a greater overall brain volume, but a decreased connection between the hemispheres.
A study conducted in 1996 found no effects on mood or behavior from the administration of supraphysiologic doses of Testosterone for 10 weeks to healthy men.
The literature suggests that attention, memory, and spatial ability are key cognitive functions affected by testosterone in humans, though the literature is rather sparse. Preliminary evidence suggests that low testosterone levels may be a risk factor for cognitive decline and possibly for dementia of the Alzheimer?s type, a key argument in Life Extension Medicine for the use of testosterone in anti-aging therapies. Much of the literature, however, suggests a curvilinear or even quadratic relationship between spatial performance and circulating testosterone, where both hypo- and hypersecretion of circulating androgens have negative effects on cognition and cognitively-modulated aggressivity, as detailed above.
Contrary to what has been postulated in outdated studies and by certain sections of the media, aggressive behaviour is not typically seen in hypergonadal men who have their testosterone replaced adequately to the eugonadal/normal range. In fact aggressive behaviour has been associated with hypogonadism and low testosterone levels and it would seem as though supraphysiological and low levels of testosterone and hypogonadism cause mood disorders and aggressive behaviour, with eugondal/normal testosterone levels being important for mental well-being. Testosterone depletion is a normal consequence of aging in men. One consequence of this is an increased risk for the development of Alzheimer?s Disease (Pike et al, 2006, Rosario 2004).
Mechanism
The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors.
Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5α-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5-alpha reductase. DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects. It is important to note that if there is a 5-alpha reductase deficiency, the body (of a human) will continue growing into a female with testicles.
Androgen receptors occur in many different vertebrate body system tissues, and both males and females respond similarly to similar levels. Greatly differing amounts of testosterone prenatally, at puberty, and throughout life account for a share of biological differences between males and females.
The bones and the brain are two important tissues in humans where the primary effect of testosterone is by way of aromatization to estradiol. In the bones, estradiol accelerates maturation of cartilage into bone, leading to closure of the epiphyses and conclusion of growth. In the central nervous system, testosterone is aromatized to estradiol. Estradiol rather than testosterone serves as the most important feedback signal to the hypothalamus (especially affecting LH secretion). In many mammals, prenatal or perinatal «masculinization» of the sexually dimorphic areas of the brain by estradiol derived from testosterone programs later male sexual behavior.
The human hormone testosterone is produced in greater amounts by males, and less by females. The human hormone estrogen is produced in greater amounts by females, and less by males. Testosterone causes the appearance of masculine traits (i.e., deepening voice, pubic and facial hairs, muscular build, etc.) Like men, women rely on testosterone to maintain libido, bone density and muscle mass throughout their lives. In men, inappropriately high levels of estrogens lower testosterone, decrease muscle mass, stunt growth in teenagers, introduce gynecomastia, increase feminine characteristics, and decrease susceptibility to prostate cancer, reduces libido and causes erectile dysfunction and can cause excessive sweating and hot flushes. However, an appropriate amount of estrogens is required in the male in order to ensure well-being, bone density, libido, erectile function, etc.
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